Understand the signs and symptoms
Did you know that some seemingly unrelated signs and symptoms could be caused by ATTR-CM? Your body may be sending you a message.
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FATIGUE11
(excessive tiredness)![Fatigue](/sites/default/files/inline-images/circle-1_0.png)
TENDON RUPTURE6,14
(eg, biceps, Achilles tendon)![Tendon Rupture](/sites/default/files/inline-images/circle-5_0.png)
GASTROINTESTINAL ISSUES3,11,19
(eg, diarrhea, constipation, nausea, or feeling full quickly)![Gastrointestinal Issues](/sites/default/files/inline-images/circle-8.png)
SHOULDER, HIP, AND/OR KNEE PAIN21
![Shoulder, Hip, and/or Knee Pain](/sites/default/files/inline-images/knee-pain-image.png)
SWELLING IN LOWER LEGS16
(known as peripheral edema)![Swelling in Lower Legs](/sites/default/files/inline-images/circle-leg.png)
![body](/sites/default/files/inline-images/BODY_0.png)
![Eye Disorders](/sites/default/files/inline-images/circle-2.png)
EYE DISORDERS12,13
(eg, glaucoma)![Shortness of Breath](/sites/default/files/inline-images/circle-3.png)
SHORTNESS OF BREATH3,15
![Irregular Heartbeat](/sites/default/files/inline-images/circle-4.png)
IRREGULAR HEARTBEAT1,16-18
(known as cardiac arrhythmia)![Bilateral Carpal Tunnel Syndrome](/sites/default/files/inline-images/Bilateral-tunnel-syndrome-image.png)
BILATERAL CARPAL TUNNEL SYNDROME1,6,20
(numbness, tingling, or pain in your fingers)![Pain or Numbness in Lower Back/Legs Due to Narrowing of Lower Spine](/sites/default/files/inline-images/pain-in-leg-image.png)
PAIN OR NUMBNESS IN LOWER BACK/LEGS DUE TO NARROWING OF LOWER SPINE6,13
(known as lumbar spinal stenosis)![Decreased or Strange Tingling Sensation/Pain in Toes/Feet](/sites/default/files/inline-images/circle-11.png)
DECREASED OR STRANGE TINGLING SENSATION/PAIN IN TOES/FEET3,22
(known as peripheral neuropathy)![](/sites/default/files/2021-11/circle-1.png)
FATIGUE11
(excessive tiredness)
![](/sites/default/files/2021-11/circle-2.png)
EYE DISORDERS12,13
(ie, glaucoma)
![](/sites/default/files/2021-11/circle-3.png)
SHORTNESS OF BREATH3,15
![](/sites/default/files/2021-11/circle-4.png)
IRREGULAR HEARTBEAT1,16-18
(known as cardiac arrhythmia)
![](/sites/default/files/2021-11/circle-5.png)
TENDON RUPTURE6,14
(eg, biceps, Achilles tendon)
![](/sites/default/files/2021-11/pain-in-leg-image.png)
PAIN OR NUMBNESS IN LOWER BACK/LEGS DUE TO NARROWING OF LOWER SPINE6,13
(known as lumbar spinal stenosis)
![](/sites/default/files/2021-11/Bilateral-tunnel-syndrome-image.png)
BILATERAL CARPAL TUNNEL SYNDROME1,6,20
(numbness, tingling, or pain in your fingers)
![](/sites/default/files/2021-11/circle-8.png)
GASTROINTESTINAL ISSUES3,11,19
(eg, diarrhea, constipation, nausea, or feeling full quickly)
![](/sites/default/files/2021-11/knee-pain-image.png)
SHOULDER, HIP, AND/OR KNEE PAIN21
![](/sites/default/files/2021-11/circle-leg.png)
SWELLING IN LOWER LEGS16
(known as peripheral edema)
![](/sites/default/files/2021-11/circle-11.png)
DECREASED OR STRANGE TINGLING SENSATION/PAIN IN TOES/FEET3,22
(known as peripheral neuropathy)
![stickynote](/sites/default/files/inline-images/when-stickynote.png)
If your doctor suspects ATTR-CM, they may conduct certain diagnostic tests.